A warning has been issued after two cases of a life-threatening infection were recorded in children at a Kent nursery.

The toddlers, who attend Little Angels Day Nursery in Northfleet, are currently in hospital suffering from meningococcal disease.

The condition can cause meningitis or sepsis and is most common in babies and young children.

Specialists from Public Health England say they are working closely with NHS partners following the outbreak.

Antibiotics and advice has been issued to those who had close contact with the children.

Dr Rachel Pudney, public health consultant for PHE South East of England said: "Meningococcal infection is comparatively rare and we do not currently suspect further cases, but it is important that everyone should be aware of the symptoms to look out for and if anyone becomes ill with symptoms of meningitis or septicaemia (blood poisoning) they should get urgent medical help right away.

"This disease can be serious, and so it is important that it is dealt with very quickly, as it can be treated most effectively in the early stages.

"People who have had prolonged, close contact with an ill person are at a slightly increased risk of becoming unwell, which is why these immediate contacts have been offered antibiotics as a precautionary measure."

Early symptoms, which may not always be present, include:

• A high temperature
• Vomiting
• Severe and worsening headache
• Stiff neck
• Joint and muscle pain
• Dislike of bright lights
• A rash that doesn’t fade when pressed with a glass
• Drowsiness that can deteriorate into a coma

Dr Putney added: "I would also urge parents to ensure their children are fully up-to-date with all childhood vaccinations – including Meningitis B, Meningitis C and Meningitis A.C, W, Y in line with current recommendations as these vaccines protect against a number of different strains of meningitis which are more common among children and young people.”

Little Angels Day Nursery were unavailable for further comment this morning but have issued a letter to parents and posted on its Facebook page about the incident.