Three people have been cut from wreckage after a crash on Seven Mile Lane, while one vehicle is reported to have left the scene.
The smash happened near Comp Lane, Offham, just before 11am.
Police, paramedics and the fire service attended and freed two men and one woman from a van and a car.
All three were taken to hospital but the extent of their injuries is not known.
A police spokesman said: "A local road closure has been enforced between Mereworth and the A20. At present, no serious injuries have been reported.
"One vehicle is reported to have left the scene of the collision and inquiries to locate this are ongoing."
The road had reopened by 1.30pm.
Three ambulances and two response cars attended, with three people taken to Tunbridge Wells hospital.
One man in his 60s had chest injuries, while a woman, also aged in her 60s, was stretchered into an ambulance with injuries including a potential chest injury.