An elderly woman died after a crash on the A299 Thanet Way near St Nicholas at Wade.
The crash, which involved a Nissan Micra and an Audi, happened on the London-bound carriageway at around 10.10pm last night.
A police spokesman said an 86-year-old woman driving the Nissan died at the scene.
The male driver of the Audi was taken to the QEQM Hospital at Margate with leg injuries. A passenger in the Audi was also hurt, although not seriously.
A police spokesman said the crash has been referred to the Independent Police Complaints Commission because a police car was on the coastbound carriageway and officers witnessed it.
The road was closed after the crash but has now reopened.
Anyone with information is urged to contact Kent Police's Serious Collision Investigation Unit on 01622 798538.